The European Agency for the Evaluation of Medicinal Products Veterinary Medicines Evaluation Unit

In pigs it is used for treatment of dysenteria due to Serpulina hyodysenteriae at a dosage of 25 mg/kg/day for 4 days for therapy. For eradication of the disease in herds treatment for 7 days and a second treatment period of 5 days after 3-4 weeks is indicated. Metronidazole is intended for use in cows with retentio secundinarum in combination with neomycine administered as intra-uterine capsules. The dosage is 2.0 g metronidazole and 1.66 g neomycine per capsule and the recommended treatment regimen is twice during 48 hours.